Free shipping on all orders over $ 500

Cercosporin

Cat. No. M10805

All AbMole products are for research use only, cannot be used for human consumption.

Cercosporin Structure
Synonym:

cgp049090

Size Price Availability Quantity
1mg USD 185  USD185 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Cercosporin is produced by the plant pathogenSporakikuchii and elsinochromes, pigments of the elsinoe family of fungi. Cercosporin is an effective photosensitizer with a short activation wavelength that is primarily suitable for surface PDT photodynamic studies (especially for the avoidance of perforation studies). Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC50 of 0.6-1.3 μM.

Chemical Information
Molecular Weight 534.51
Formula C29H26O10
CAS Number 35082-49-6
Solubility (25°C) DMSO 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Masaru Katoh. Int J Mol Med. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review)

[2] Jie Yao, et al. Oncol Lett. Overexpression of miR-506 suppresses proliferation and promotes apoptosis of osteosarcoma cells by targeting astrocyte elevated gene-1

[3] Sachiko Matsuzaki, et al. PLoS One. Involvement of the Wnt/β-catenin signaling pathway in the cellular and molecular mechanisms of fibrosis in endometriosis

[4] Ellie B M Landman, et al. Arthritis Res Ther. Small molecule inhibitors of WNT/β-catenin signaling block IL-1β- and TNFα-induced cartilage degradation

[5] Rajesh Kumar Gandhirajan, et al. Neoplasia. Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

Related PKC Products
Sapintoxin D 

Sapintoxin D is a fluorescent phorbol ester that can be used to study the activation of protein kinase C (PKC).

Bryostatin 3 

Bryostatin 3, a macrocyclic lactone, is a protein kinase C activator, with a Ki of 2.75 nM.

Ruboxistaurin mesylate

Ruboxistaurin (LY333531) mesylate is an orally active, selective and ATP competitive PKCβ inhibitor with IC50 values of 4.7 and 5.9 nM for PKCβI and PKCβII, respectively.

PKC β pseudosubstrate

PKC β pseudosubstrate is a selective cell-permeable inhibitor of PKC.

Protein Kinase C (19-31)

Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), is used as protein kinase C substrate peptide for testing the protein kinase C activity.

  Catalog
Abmole Inhibitor Catalog




Keywords: Cercosporin, cgp049090 supplier, PKC, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.