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Cerebroside B

Cat. No. M30815
Cerebroside B Structure
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Biological Activity

Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice.

Chemical Information
Molecular Weight 728.05
Formula C41H77NO9
CAS Number 88642-46-0
Form Solid
Storage Powder -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ran An, et al. Sci Rep. Isolation, purification and identification of biological compounds from Beauveria sp. and their evaluation as insecticidal effectiveness against Bemisia tabaci

[2] András Sárközy, et al. Molecules. Cerebrosides and Steroids from the Edible Mushroom Meripilus giganteus with Antioxidant Potential

[3] Nelum P K G Piyasena, et al. Nat Prod Commun. Xylactam B, A New Isobenzofuranone from an Endophytic Xylaria sp

[4] Han-Wei Liu, et al. Nat Prod Res. Steroids and phenolic constituents from the fruiting bodies of the basidiomycete Sarcodon joedes

[5] Kenji Umemura, et al. Phytopathology. Cerebroside elicitor confers resistance to fusarium disease in various plant species

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