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Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. Cefazolin has a strong effect on Gram-positive bacteria such as Staphylococcus aureus, hemolytic streptococcus, pneumococcus, diphtheria and Clostridium. Cefazolin has a strong effect on Gram-negative bacteria, especially for Klebsiella pneumoniae. Cefazolin is also effective against Escherichia coli, Proteus mirabilis and Salmonella typhi.
| Molecular Weight | 454.51 |
| Formula | C14H14N8O4S3 |
| CAS Number | 25953-19-9 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage | 2-8°C, dry, protect from light, sealed |
[2] K S Scher, et al. Am J Surg. Duration of antibiotic prophylaxis. An experimental study
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