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CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.
Molecular Weight | 471.61 |
Formula | C25H33N3O4S |
CAS Number | 1952239-59-6 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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