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CD12681 

Cat. No. M29048

All AbMole products are for research use only, cannot be used for human consumption.

CD12681  Structure

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Quality Control & Documentation
Biological Activity

CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.

Chemical Information
Molecular Weight 471.61
Formula C25H33N3O4S
CAS Number 1952239-59-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Gilles Ouvry, et al. ChemMedChem. Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis

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  Catalog
Abmole Inhibitor Catalog




Keywords: CD12681  supplier, ROR, inhibitors, activators

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