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CCT241161 is an orally active pan-RAF inhibitor with IC50s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also exhibits anticancer cell proliferative activity.
Molecular Weight | 541.62 |
Formula | C28H27N7O3S |
CAS Number | 1163719-91-2 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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