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CCT196969

Cat. No. M20609

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CCT196969 Structure

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Quality Control & Documentation
Biological Activity

CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.

Chemical Information
Molecular Weight 513.52
Formula C27H24FN7O3
CAS Number 1163719-56-9
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Agathe Reigstad, et al. PLoS One. CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells

[2] Gautham Gampa, et al. J Pharmacol Exp Ther. Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

[3] Maria Romina Girotti, et al. Cancer Cell. Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: CCT196969 supplier, Raf, inhibitors, activators

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