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CC-99677 is an oral, covalent MAPK-activated protein kinase-2 (MK2) inhibitor being developed for the study of autoimmune diseases. It is useful in both biochemical (IC50=156.3 nM) and cell-based assays (EC50=89 nM).
| Molecular Weight | 469.94 |
| Formula | C22H20ClN5O3S |
| CAS Number | 1887069-10-4 |
| Solubility (25°C) | DMSO : 37.5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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