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Caspofungin acetate

Cat. No. M3726

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Caspofungin acetate Structure
Synonym:

Cancidas

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
5mg USD 60  USD60 In stock
10mg USD 100  USD100 In stock
50mg USD 320  USD320 In stock
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Quality Control & Documentation
Biological Activity

Caspofungin exhibited similar efficacy to TMP-SMZ for enhancing survival and reducing lung edema and cyst load in a rat model of PcP, suggesting potential clinical utility against PcP. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin is at least as effective as amphotericin B for the treatment of invasive candidiasis and, more specifically, candidemia. Caspofungin may be considered as a component of combination antifungal regimens. Caspofungin represents a significant advance in the care of patients with serious fungal infections.

Chemical Information
Molecular Weight 1213.42
Formula C52H88N10O15.2(C2H4O2)
CAS Number 179463-17-3
Solubility (25°C) Water 100 mg/mL
DMSO 90 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Sun P, et al. Med Mycol. Efficacy of caspofungin, a 1,3-β-D-glucan synthase inhibitor, on Pneumocystis carinii pneumonia in rats.

[2] Morrison VA. Expert Rev Anti Infect Ther. Caspofungin: an overview.

[3] Mora-Duarte J, et al. N Engl J Med. Comparison of caspofungin and amphotericin B for invasive candidiasis.

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Keywords: Caspofungin acetate, Cancidas supplier, Anti-infection, inhibitors, activators

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