Free shipping on all orders over $ 500

Carumonam

Cat. No. M40863

All AbMole products are for research use only, cannot be used for human consumption.

Carumonam Structure
Synonym:

AMA-1080; Ro 17-2301

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Carumonam (AMA-1080) is a sulfonated monocyclic β-lactam antibiotic from Chromobacterium purpureum that targets penicillin-binding proteins (PBPs), is active against aerobic Gram-negative bacteria and is resistant to β-lactamase-mediated hydrolysis.

Chemical Information
Molecular Weight 466.4
Formula C12H14N6O10S2
CAS Number 87638-04-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R J Fass et al. Antimicrob Agents Chemother. In vitro activity of carumonam

[2] Y Kita et al. Antimicrob Agents Chemother. Comparative pharmacokinetics of carumonam and aztreonam in mice, rats, rabbits, dogs, and cynomolgus monkeys

[3] A I Hoepelman et al. Antimicrob Agents Chemother. Carumonam (Ro 17-2301; AMA-1080) compared with gentamicin for treatment of complicated urinary tract infections

[4] A Saito. Jpn J Antibiot. [Carumonam]

[5] H Edelstein et al. Antimicrob Agents Chemother. Carumonam versus ceftazidime for urinary tract infections

Related Antibiotic Products
Puromycin-d3

Puromycin-d3 is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

BSH-IN-1

BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively.

AAA-10

AAA-10 is an orally active gut bacterial bile salt hydrolases (BSH) inhibitor, with IC50s of 10 nM, 80 nM against B. theta rBSH and B. longum rBSH respectively.

Gut restricted-7

Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice.

N-Hydroxypipecolic acid

N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection.

  Catalog
Abmole Inhibitor Catalog




Keywords: Carumonam, AMA-1080; Ro 17-2301 supplier, Antibiotic, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.