Free shipping on all orders over $ 500

Carnosol

Cat. No. M4389

All AbMole products are for research use only, cannot be used for human consumption.

Carnosol Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 70  USD70 In stock
25mg USD 140  USD140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Carnosol is a naturally occurring phyto polyphenol[1]or phenolic diterpene, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent. Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis. The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.

Chemical Information
Molecular Weight 330.42
Formula C20H26O4
CAS Number 5957-80-2
Storage -20°C, protect from light
References

[1] Huang SC, et al. Biochem Pharmacol. Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappa B and c-Jun.

[2] Lo AH, et al. Carcinogenesis. Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kappaB in mouse macrophages.

Related Immunology/Inflammation Products
Aloe Polysaccharide

Aloe Polysaccharides are the primary bioactive components of aloe vera gel, primarily found in the gel-like portion of the aloe vera leaf, specifically the transparent, viscous section enclosed by the leaf epidermis. Aloe polysaccharides are a large class of macromolecular compounds with diverse physiological functions, primarily composed of mannose, galactose, glucose, xylose, arabinose, and rhamnose, with mannose, galactose, and glucose being the most abundant. They exhibit various bioactivities, including antibacterial and anti-inflammatory effects, antiviral activity, immune modulation, antitumour properties, radiation protection, antioxidant properties, and hypoglycaemic effects.

Terminalia Chebula Extract

Terminalia Chebula Extract is extracted from Terminalia Chebula, which has antioxidant, hepatoprotective, neuroprotective, cytotoxic, antidiabetic, and anti-inflammatory activities.

SMS121

SMS121 is a novel CD36 inhibitor. SMS121 reduced the uptake of fatty acid into AML cells that could be reversed by addition of free fatty acids and caused decreased cell viability.

Rolistobart

Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody.

Gemtuzumab

Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for the synthesis of antibody-drug conjugate (ADC) Gemtuzumab ozogamicin.

  Catalog
Abmole Inhibitor Catalog




Keywords: Carnosol supplier, Immunology/Inflammation, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.