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Carmustine

Cat. No. M3273

All AbMole products are for research use only, cannot be used for human consumption.

Carmustine Structure
Synonym:

NSC-409962

Size Price Availability Quantity
10mM*1mL in DMSO USD 30  USD30 In stock
1mg USD 20  USD20 In stock
5mg USD 30  USD30 In stock
10mg USD 45  USD45 In stock
50mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Carmustine (BiCNU) is a cell-cycle phase nonspecific alkylating antineoplastic agent with ED50 ranging from 5.0 µM to 11.9 µM. It is used in the treatment of several types of brain cancer (including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma and lymphoma (Hodgkin’s and non-Hodgkin). In a study, three lines with O6-AGT activity below 25 fmol/mg protein had carmustine ED50 values ranging from 5.0 µM to 11.9 µM.

Chemical Information
Molecular Weight 214.05
Formula C5H9Cl2N3O2
CAS Number 154-93-8
Solubility (25°C) DMSO
Storage -20°C, protect from light
References

[1] Yun-Dong Zhang, et al. Efficacy and safety of carmustine wafers in the treatment of glioblastoma multiforme: a systematic review

[2] David Y Pereira, et al. Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas

[3] Steven H Lin, et al. Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies

[4] Alison B Fleming, et al. Pharmacokinetics of the carmustine implant

[5] N Burnham, et al. BCNU (carmustine)

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Keywords: Carmustine, NSC-409962 supplier, DNA Alkylator/Crosslinker, inhibitors, activators

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