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Carbazeran is an Aldehyde oxidase (AO) substrate and a phosphodiesterase inhibitor that produces concentration-dependent positive inotropic responses. In humans, the compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO.
| Molecular Weight | 360.41 |
| Formula | C18H24N4O4 |
| CAS Number | 70724-25-3 |
| Solubility (25°C) | DMSO: ≥2 mg/mL at warmed |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] B Kaye, et al. Oxidative metabolism of carbazeran in vitro by liver cytosol of baboon and man
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