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Cadisegliatin (TTP-399)

Cat. No. M21626

All AbMole products are for research use only, cannot be used for human consumption.

Cadisegliatin (TTP-399) Structure
Synonym:

TTP-399

Size Price Availability
5mg USD 300  USD300 1-2 Weeks
10mg USD 480  USD480 1-2 Weeks
25mg USD 950  USD950 1-2 Weeks
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Quality Control & Documentation
Biological Activity

Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes. Cadisegliatin did not cause hypoglycemia, had no detrimental effect on plasma lipids or liver enzymes, and did not increase blood pressure, highlighting the importance of tissue selectivity and preservation of physiological regulation when targeting key metabolic regulators such as GK.

Chemical Information
Molecular Weight 455.63
Formula C21H33N3O4S2
CAS Number 859525-02-3
Form Solid
Solubility (25°C) DMSO ≥ 90 mg/mL
Storage 4°C, protect from light
Related Glucokinase (GK) Products
AZD1092

AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM.

GKM-001

GKM-001 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes.

TMG-123

TMG-123 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes.

PB-201

PB-201 is a glucokinase activator (GKA) that can be used in studies related to type 2 diabetes.

MK-0941 free base 

MK-0941 free base is an orally active glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 free base exhibits strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.

  Catalog
Abmole Inhibitor Catalog




Keywords: Cadisegliatin (TTP-399), TTP-399 supplier, Glucokinase (GK), inhibitors, activators

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