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CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1. CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes.
| Molecular Weight | 360.32 |
| CAS Number | 1673534-76-3 |
| Solubility (25°C) | DMSO 28.5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Bogdan Musielak, et al. CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
[3] Christine Cuyler, et al. Muskox status, recent variation, and uncertain future
[4] Raphal Paris, et al. Explosive eruption, flank collapse and megatsunami at Tenerife ca. 170 ka
[5] Toru Odate, et al. Anatomy of the levator claviculae, with an overview and a literature survey
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