Butoconazole is an imidazole antifungal used in gynecology.
|Solubility (25°C)||DMSO 82 mg/mL|
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 Bianca-Maria Ţuchiu, et al. ACS Omega. N-Methylfulleropyrrolidine-Based Multimode Sensor for Determination of Butoconazole Nitrate
 No authors listed. Butoconazole
 D Brown, et al. J Reprod Med. Butoconazole nitrate 2% for vulvovaginal candidiasis. New, single-dose vaginal cream formulation vs. seven-day treatment with miconazole nitrate. Gynazole 1 Study Group
 D M Tatum, et al. Infect Control Hosp Epidemiol. Butoconazole nitrate
 R H Kaufman, et al. J Reprod Med. Comparison of three-day butoconazole treatment with seven-day miconazole treatment for vulvovaginal candidiasis
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