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Busulfan

Cat. No. M3356

All AbMole products are for research use only, cannot be used for human consumption.

Busulfan Structure
Size Price Availability Quantity
500mg USD 55  USD55 In stock
1g USD 80  USD80 In stock
5g USD 160  USD160 In stock
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Quality Control & Documentation
Biological Activity

Busulfan is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate. Its main uses are in bone marrow transplantation, especially in chronic myelogenous leukemia (CML), where it is used as a conditioning drug. Busulfan can control tumor burden but cannot prevent transformation or correct cytogenic abnormalities. Though not as common, it may also be used for chronic lymphocytic leukemia (CLL).

Product Citations
Chemical Information
Molecular Weight 246.3
Formula C6H14O6S2
CAS Number 55-98-1
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ning Qu, et al. Int J Mol Sci. Gosha-Jinki-Gan Recovers Spermatogenesis in Mice with Busulfan-Induced Aspermatogenesis

[2] YuSheng Qin, et al. PLoS One. Testicular Busulfan Injection in Mice to Prepare Recipients for Spermatogonial Stem Cell Transplantation Is Safe and Non-Toxic

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Keywords: Busulfan supplier, DNA Alkylator/Crosslinker, inhibitors, activators

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