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Bucillamine

Cat. No. M40860

All AbMole products are for research use only, cannot be used for human consumption.

Bucillamine Structure
Synonym:

SA96; Thiobutarit

Price and Availability

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Quality Control & Documentation
Biological Activity

Bucillamine is an orally bioavailable endogenous derivative of the amino acid cysteine with potential antioxidant and anti-inflammatory activity. Upon oral administration, Bucillamine rapidly enters cells via the same pathway as cysteine, complementing the thiol groups in glutathione ( GSH ), thereby increasing intracellular GSH levels and GSH activity.GSH is an antioxidant that plays an important protective role in oxidative stress and injury.

Chemical Information
Molecular Weight 223.31
Formula C7H13NO3S2
CAS Number 65002-17-7
Form Solid
Storage 4°C, protect from light
References

[1] Keitaro Nakamoto et al. J Gen Fam Med. Bucillamine-induced interstitial pneumonitis

[2] T Yanagishita et al. J Eur Acad Dermatol Venereol. Bucillamine-induced pemphigus vulgaris

[3] Daiki Nakagomi et al. Rheumatol Int. Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 36 reported cases

[4] Atsuko Izumi et al. J Dermatol. Bucillamine-induced toxic epidermal necrolysis and fixed drug eruption

[5] Lawrence D Horwitz. Cardiovasc Drug Rev. Bucillamine: a potent thiol donor with multiple clinical applications

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Keywords: Bucillamine, SA96; Thiobutarit supplier, Anti-infection, inhibitors, activators

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