Free shipping on all orders over $ 500

Bucillamine

Cat. No. M40860
Bucillamine Structure
Synonym:

SA96; Thiobutarit

Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Bucillamine is an orally bioavailable endogenous derivative of the amino acid cysteine with potential antioxidant and anti-inflammatory activity. Upon oral administration, Bucillamine rapidly enters cells via the same pathway as cysteine, complementing the thiol groups in glutathione ( GSH ), thereby increasing intracellular GSH levels and GSH activity.GSH is an antioxidant that plays an important protective role in oxidative stress and injury.

Chemical Information
Molecular Weight 223.31
Formula C7H13NO3S2
CAS Number 65002-17-7
Form Solid
Storage 4°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related Anti-infection Products
AV5124

AV5124 is a Cap-dependent endonuclease (CEN) inhibitor for studies related to respiratory diseases.

ML188

ML188 is a first-in-class probe and also a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. antiviral activity.

Phloretic acid

Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

Neochlorogenic acid methyl ester

Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is an HBV inhibitor.

Methyl tanshinonate

Methyl tanshinonate is a potent inhibitor of Mpro enzyme in SARS-CoV (IC50 = 21.1 µM).

  Catalog
Abmole Inhibitor Catalog




Keywords: Bucillamine, SA96; Thiobutarit supplier, Anti-infection, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.