Free shipping on all orders over $ 500

BS-194 

Cat. No. M27775

All AbMole products are for research use only, cannot be used for human consumption.

BS-194  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

BS-194 is an orally active, selective and potent CDK inhibitor. BS-194 inhibits CDK2, CDK1, CDK5, CDK7, CDK9 (IC50s: 3, 30, 30, 250, and 90 nM respectively). BS-194 potently inhibits cancer cells proliferation. BS-194 can be used in the research of cancers like breast cancer, colon cancer.

Chemical Information
Molecular Weight 385.46
Formula C20H27N5O3
CAS Number 1092443-55-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Sunil Kumar Tripathi, et al. J Mol Recognit. Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach

[2] Dean A Heathcote, et al. J Med Chem. A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

Related CDK Products
(E/Z)-Zotiraciclib citrate

(E/Z)-Zotiraciclib citrate is a potent CDK2, JAK2, and FLT3 inhibitor.

Abemaciclib metabolites M2

Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50 values of 1.2 and 1.3 nM, respectively.

CDK9-IN-1

CDK9-IN-1 is a novel, selective CDK9 inhibitor, with an IC50 of 39 nM for CDK9/CycT1, it can be used for the research of HIV infection.

XO44

XO44 (PF-6808472) is a broad-spectrum covalent kinase probe.

ML 315 

ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: BS-194  supplier, CDK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.