All AbMole products are for research use only, cannot be used for human consumption.
Brensocatib (AZD7986) is a first-in-class, oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively.
| Molecular Weight | 420.46 |
| CAS Number | 1802148-05-5 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] James D Chalmers, et al. Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis
[5] Daniela F Quail, et al. Neutrophil phenotypes and functions in cancer: A consensus statement
| Related Dipeptidyl Peptidase Products |
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| K579
K579 is a potent and orally active dipeptidyl peptidase IV inhibitor. |
| Retagliptin
Retagliptin (SP2086) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. |
| Cofrogliptin
Cofrogliptin (HSK7653), a tetrahydropyran derivative, is a potent oral dipeptidyl aminopeptidase 4 (DPP-4) inhibitor with Long-acting antidiabetic efficacy. |
| Retagliptin phosphate
Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. |
| Gly-Pro-pNA hydrochloride
Gly-Pro-pNA hydrochloride is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidase IV and dipeptidyl peptidase IX. Gly-Pro-pNA hydrochloride is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA can be used to screen for DPP IV inhibitors. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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