Certificate of Analysis

 

Product Name: Brensocatib
Catalog Number: M14317
CAS Number: 1802148-05-5

Physical and Chemical Properties
Molecular Weight: 420.46
Solubility: DMSO ≥ 90 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Brensocatib Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.