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BMT-090605 hydrochloride is a potent, selective the adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 value of 0.6 nM. BMT-090605 hydrochloride shows antinociceptive activity. BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50 values of 45 nM and 60 nM, respectively. BMT-090605 hydrochloride can be used for the research of neuropathic pain.
| Molecular Weight | 400.9 |
| Formula | C21H25ClN4O2 |
| CAS Number | 2231664-45-0 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Chuangchuang Xu, et al. Org Biomol Chem. Metal-free and regiospecific synthesis of 3-arylindoles
[2] No authors listed. Carteolol
[5] S Groszkowski, et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines
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