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BMS-986365

Cat. No. M54872

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BMS-986365 Structure
Synonym:

CC-94676

Size Price Availability Quantity
5mg USD 580  USD580 In stock
10mg USD 930  USD930 In stock
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Quality Control & Documentation
Biological Activity

BMS-986365 (CC-94676) is a selective heterobifunctional ligand-directed degrader (LDD) targeting the androgen receptor (AR). BMS-986365 is a highly potent and selective AR degrader that induces rapid and deep degradation of both wildtype and mutant forms of the receptor residing in either the cytoplasmic or nuclear compartments of the cell. BMS-986365 (CC-94676) demonstrated significant in vivo potency, degrading AR, inhibiting AR signaling, and inhibiting tumor growth in animal models of advanced prostate cancer.

Chemical Information
Molecular Weight 818.91
Formula C41H45F3N8O5S
CAS Number 2446928-30-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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Keywords: BMS-986365, CC-94676 supplier, Androgen Receptor, inhibitors, activators

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