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BMS-466442 

Cat. No. M28653

All AbMole products are for research use only, cannot be used for human consumption.

BMS-466442  Structure

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Quality Control & Documentation
Biological Activity

BMS-466442 is a potent and selective inhibitor of asc-1 (alanine serine cysteine transporter-1), with an IC50 of 11 nM. BMS-466442 inhibits [3H] D-serine uptake into rat brain synaptosomes, with an IC50 of 400 nM. BMS-466442 can be used for schizophrenia research.

Chemical Information
Molecular Weight 538.59
Formula C31H30N4O5
CAS Number 1598424-76-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Rini Arianti, et al. FEBS Lett. ASC-1 transporter-dependent amino acid uptake is required for the efficient thermogenic response of human adipocytes to adrenergic stimulation

[2] Ivan R Torrecillas, et al. ACS Chem Neurosci. Inhibition of the Alanine-Serine-Cysteine-1 Transporter by BMS-466442

[3] Jeffrey M Brown, et al. J Neurochem. In vitro Characterization of a small molecule inhibitor of the alanine serine cysteine transporter -1 (SLC7A10)

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  Catalog
Abmole Inhibitor Catalog




Keywords: BMS-466442  supplier, Dopamine Transporter, inhibitors, activators

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