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BMS-214662 is an orally available, potent and selective inhibitor of farnesyltransferase that reduces Ras prenylation in NF90-8 and ST88-14 sheath tumor (MPNST) cell lines. BMS-214662 induces apoptosis in cancer cell lines, and potently inhibits growth of human tumor xenografts.
| Molecular Weight | 526.07 |
| Formula | C25H23N5O2S2.HCl |
| CAS Number | 195981-08-9 |
| Solubility (25°C) | Water 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] M Bays, et al. Gateways to clinical trials
[2] M Bayes, et al. Gateways to clinical trials
[3] M Bays, et al. Gateways to clinical trials
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