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Bisindolylmaleimide X hydrochloride

Cat. No. M13855

All AbMole products are for research use only, cannot be used for human consumption.

Bisindolylmaleimide X hydrochloride Structure
Synonym:

BIM-X hydrochloride; Ro31-8425 hydrochloride

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1mg USD 90  USD90 In stock
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Biological Activity

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM.

Chemical Information
Molecular Weight 460.96
CAS Number 145317-11-9
Solubility (25°C) DMSO 20.83 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Najwa Skafi, et al. J Cell Physiol. Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease

[2] Jose M Jimenez-Lopez, et al. J Pharmacol Exp Ther. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells

[3] C S Chew, et al. Am J Physiol. Ca2+-independent protein kinase C isoforms may modulate parietal cell HCl secretion

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  Catalog
Abmole Inhibitor Catalog




Keywords: Bisindolylmaleimide X hydrochloride, BIM-X hydrochloride; Ro31-8425 hydrochloride supplier, PKC, inhibitors, activators

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