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BIIB091

Cat. No. M21222

All AbMole products are for research use only, cannot be used for human consumption.

BIIB091  Structure

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Quality Control & Documentation
Biological Activity

The reversible BTK kinase inhibitor BIIB091 is a highly selective phase I clinical candidate compound for multiple sclerosis.

Chemical Information
Molecular Weight 542.64
Formula C28H34N10O2
CAS Number 2247614-80-6
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anastasia Geladaris, et al. CNS Drugs. Bruton's Tyrosine Kinase Inhibitors in Multiple Sclerosis: Pioneering the Path Towards Treatment of Progression?

[2] Brian T Hopkins, et al. J Med Chem. Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis

[3] Eris Bame, et al. Clin Transl Immunology. Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: BIIB091 supplier, BTK, inhibitors, activators

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