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BIBF0775

Cat. No. M10596

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BIBF0775 Structure
Synonym:

BIBF-0775

Size Price Availability
5mg USD 180  USD180 4-7 Days
25mg USD 460  USD460 4-7 Days
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Quality Control & Documentation
Biological Activity

BIBF0775 is a potent and selective inhibitor of the transforming growth factor β receptor I (TGFβRI, Alk5) with an IC50 of 34 nM. BIBF0775 soaked into the kinase domain of TGFβRI.

Chemical Information
Molecular Weight 494.63
Formula C31H34N4O2
CAS Number 334951-90-5
Solubility (25°C) DMSO 48 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gerald J Roth, et al. J Med Chem. Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI)

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  Catalog
Abmole Inhibitor Catalog




Keywords: BIBF0775, BIBF-0775 supplier, TGF-β Receptor, inhibitors, activators

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