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Betaine hydrochloride is a non-essential nutrient and a source of hydrochloric acid, a naturally occurring chemical in the stomach that helps digest food by breaking up fats and proteins. In particular, Betaine is necessary for adequate absorption of protein, calcium, vitamin B12 and iron. It is also known as hydrochloric acid and stomach acid. The low pH of the stomach’s hydrochloric acid also destroys ingested bacteria and microorganisms. Besides, the addition of betaine to polymerase chain reactions improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions. The addition of betaine has been reported to enhance the specificity of the polymerase chain reaction by eliminating the base pair composition dependence of DNA melting.
| Molecular Weight | 153.61 |
| Formula | C5H11NO2.HCl |
| CAS Number | 590-46-5 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Guangfu Zhao, et al. Betaine in Inflammation: Mechanistic Aspects and Applications
[3] Huibin Zou, et al. The metabolism and biotechnological application of betaine in microorganism
[4] Christopher R Day, et al. Betaine chemistry, roles, and potential use in liver disease
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