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β-Muricholic acid is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.
Molecular Weight | 408.58 |
Formula | C24H40O5 |
CAS Number | 2393-59-1 |
Solubility (25°C) | Soluble in DMSO |
Storage | 2-8°C |
[3] Ting Fu, et al. Cell. FXR Regulates Intestinal Cancer Stem Cell Proliferation
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