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Beraprost sodium is a chemically stable analog of prostacyclin PGI2. As other prostanoids, beraprost is a potent vasodilator and possesses antithrombotic, antiproliferative and anti-inflammatory properties. Beraprost sodium activates prostaglandin I (IP) receptor, which is coupled with Gs proteins and activates adenylate cyclase. It has been studied for the treatment of pulmonary hypertension.
| Molecular Weight | 420.47 |
| Formula | C24H29O5 · Na |
| CAS Number | 88475-69-8 |
| Solubility (25°C) | Water: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] A Sugawara, et al. Novel effects of beraprost sodium on vasculatures
[4] S Nishio, et al. Research and development of beraprost sodium, a new stable PGI2 analogue
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