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Benfotiamine

Cat. No. M29423

All AbMole products are for research use only, cannot be used for human consumption.

Benfotiamine Structure
Synonym:

S-Benzoylthiamine O-monophosphate

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Quality Control & Documentation
Biological Activity

Benfotiamine (S-Benzoylthiamine O-monophosphate) is an analog of vitamin B1 with higher absorption and bioavailability than vitamin B1, and is commonly used as a food supplement for diabetic complications. Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage.

Chemical Information
Molecular Weight 466.45
Formula C19H23N4O6PS
CAS Number 22457-89-2
Form Solid
Solubility (25°C) DMSO ≥ 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kieran V Allowitz, et al. Future Med Chem. Therapeutic potential of vitamin B1 derivative benfotiamine from diabetes to COVID-19

[2] Gidon J Bönhof, et al. BMJ Open. BOND study: a randomised double-blind, placebo-controlled trial over 12 months to assess the effects of benfotiamine on morphometric, neurophysiological and clinical measures in patients with type 2 diabetes with symptomatic polyneuropathy

[3] Margaux Sambon, et al. Int J Mol Sci. Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine

[4] Gary E Gibson, et al. J Alzheimers Dis. Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial

[5] V Raj, et al. Eur Rev Med Pharmacol Sci. Therapeutic potential of benfotiamine and its molecular targets

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Keywords: Benfotiamine, S-Benzoylthiamine O-monophosphate supplier, inhibitors, activators

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