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BD 1063 dihydrochloride

Cat. No. M6496

All AbMole products are for research use only, cannot be used for human consumption.

BD 1063 dihydrochloride Structure
Synonym:

BD1063 2HCl

Size Price Availability Quantity
10mg USD 110  USD110 In stock
25mg USD 240  USD240 In stock
50mg USD 430  USD430 In stock
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Quality Control & Documentation
Biological Activity

BD 1063 dihydrochloride is a σ1 receptor antagonist, approximately 50-fold selective over σ2 sites and ≥100-fold selective over opioid, PCP, muscarinic, dopamine, α1, α2, β adrenoceptor, 5-HT1 and 5-HT2 receptors. Prevents hyperlocomotion following cocaine administration in mice.

Chemical Information
Molecular Weight 346.13
Formula C13H18Cl2N2.2HCl
CAS Number 206996-13-6
Form Solid
Solubility (25°C) Water ≥ 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Valentina Sabino, et al. Neuropsychopharmacology. The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

[2] Auten, et al. J Pharmacol Exp Ther. Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats.

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Keywords: BD 1063 dihydrochloride, BD1063 2HCl supplier, Sigma Receptor, inhibitors, activators

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