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BAM15

Cat. No. M8653

All AbMole products are for research use only, cannot be used for human consumption.

BAM15 Structure
Size Price Availability Quantity
5mg USD 70  USD70 In stock
10mg USD 110  USD110 In stock
25mg USD 220  USD220 In stock
50mg USD 350  USD350 In stock
100mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

BAM15 is a cell penetrant and potent uncoupler of oxidative phosphorylation in mitochondria that that does not depolarizes the plasma membrane. BAM15 protects mice from acute renal ischemic-reperfusion injury.

Chemical Information
Molecular Weight 340.29
Formula C16H10F2N6O
CAS Number 210302-17-3
Solubility (25°C) DMSO: 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cong Phi Dang, et al. BAM15, a Mitochondrial Uncoupling Agent, Attenuates Inflammation in the LPS Injection Mouse Model: An Adjunctive Anti-Inflammation on Macrophages and Hepatocytes

[2] Alexander M Firsov, et al. Protonophoric action of BAM15 on planar bilayers, liposomes, mitochondria, bacteria and neurons

[3] Christopher L Axelrod, et al. BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control

[4] Stephanie J Alexopoulos, et al. Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

[5] Mingjun Tang, et al. BAM15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue

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Keywords: BAM15 supplier, inhibitors, activators

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