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Azeliragon

Cat. No. M9483

All AbMole products are for research use only, cannot be used for human consumption.

Azeliragon Structure
Synonym:

TTP488; PF-04494700

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
2mg USD 35  USD35 In stock
5mg USD 50  USD50 In stock
10mg USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

Azeliragon is a potent and orally active RAGE inhibitor. Azeliragon can cross the blood-brain barrier (BBB).

Chemical Information
Molecular Weight 532.12
Formula C32H38ClN3O2
CAS Number 603148-36-3
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Burstein AH, et al. Clin Pharmacol D ruq Dev. Assessment of Azeliragon QTc Liability Through Integrated, Model-Based Concentration QTc Analysis.

[2] Burstein AH, et al. J Prev Alzheimers Dis. Development of Azeliragon, an Oral Small Molecule Antagonist of the Receptor for Advanced Glycation Endproducts, for the Potential Slowing of Loss of Cognition in Mild Alzheimer's Disease.

[3] Bongarzone S, et al. J Med Chem. Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective.

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  Catalog
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Keywords: Azeliragon, TTP488; PF-04494700 supplier, Amyloid, inhibitors, activators

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