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AZD1656

Cat. No. M10305

All AbMole products are for research use only, cannot be used for human consumption.

AZD1656 Structure
Synonym:

AZD-1656

Size Price Availability Quantity
1mg USD 340  USD340 In stock
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Quality Control & Documentation
Biological Activity

AZD1656 is a potent, selective and orally active glucokinase (GK) activator, with an EC50 of 60 nM.

Chemical Information
Molecular Weight 478.51
Formula C24H26N6O5
CAS Number 919783-22-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brian E Ford, et al. Diabetes Obes Metab. Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge

[2] Terri Mitchard, et al. Birth Defects Res B Dev Reprod Toxicol. The novel use of a heterozygous knockout mouse for embryofetal development assessment of a glucokinase activator

Related Glucokinase (GK) Products
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AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM.

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GKM-001 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes.

TMG-123

TMG-123 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes.

PB-201

PB-201 is a glucokinase activator (GKA) that can be used in studies related to type 2 diabetes.

MK-0941 free base 

MK-0941 free base is an orally active glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 free base exhibits strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.

  Catalog
Abmole Inhibitor Catalog




Keywords: AZD1656, AZD-1656 supplier, Glucokinase (GK), inhibitors, activators

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