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AZ 1729

Cat. No. M21374

All AbMole products are for research use only, cannot be used for human consumption.

AZ 1729 Structure

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Quality Control & Documentation
Biological Activity

AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator that acts as a direct transmutation agonist and a positive transmutation modulator.AZ1729 increases the activity of endogenous short-chain fatty acid propionate in the Gi-mediated pathway but not in the Gq/G11-transduced pathway.

Chemical Information
Molecular Weight 369.42
Formula C18H16FN5OS
CAS Number 2016864-46-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Michael Wang, et al. J Clin Oncol. Three-Year Follow-Up of KTE-X19 in Patients With Relapsed/Refractory Mantle Cell Lymphoma, Including High-Risk Subgroups, in the ZUMA-2 Study

[2] Robin Kate Kelley, et al. J Clin Oncol. Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study

[3] Winsor Chen, et al. Vasc Endovascular Surg. Aneurysmal Degeneration After Paclitaxel-Eluting Balloon Angioplasty

[4] Jessica E Tierney, et al. Science. Past climates inform our future

[5] Mark Z Wu, et al. Radiology. CT in adults: systematic review and meta-analysis of interpretation discrepancy rates

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Keywords: AZ 1729 supplier, inhibitors, activators

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