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Aurothiomalate sodium is a potent and selective oncogenic PKCι signaling inhibitor. Aurothiomalate sodium inhibits tumor cell proliferation and not cell apoptosis. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium, an anti-rheumatoid agent, exhibits potent anti-tumor activity.
| Formula | C4H6O4S.Au.xNa |
| CAS Number | 12244-57-4 |
| Form | Solid |
| Solubility (25°C) | Water 250 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
[2] D Biasi, et al. Clin Rheumatol. Sodium aurothiomalate-induced paniculitis
[4] D A Harvey, et al. Lancet. Sodium aurothiomalate is a mixture
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