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Aurintricarboxylic acid (ATA) is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM.
| Molecular Weight | 422.34 |
| Formula | C22H14O9 |
| CAS Number | 4431-00-9 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related P2 Receptor Products |
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| NF449
NF449 is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. |
| NF279
NF279 is a potent selective and reversible P2X1 receptor antagonist, with an IC50 of 19 nM. |
| NF110
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| PSB-12062
PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4. |
| NF449 octasodium
NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. |
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