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Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability. Aureobasidin A (AbA) inhibits the activity of inositol phosphorylceramide (IPC) synthetase, which is dependent on fungal growth, and interferes with sphingolipid synthesis, thereby further killing the strain.
mSystems. 2022 Oct 20;e0053922.
Systematic Metabolic Profiling Identifies De Novo Sphingolipid Synthesis as Hypha Associated and Essential for Candida albicans Filamentation
Aureobasidin A purchased from AbMole
| Molecular Weight | 1101.43 |
| Formula | C60H92N8O11 |
| CAS Number | 127785-64-2 |
| Solubility (25°C) | Soluble in methanol |
| Storage | 4°C, protect from light, dry, sealed |
[2] Adriana M Rauseo, et al. Hope on the Horizon: Novel Fungal Treatments in Development
[4] Sabrina Sonda, et al. Inhibitory effect of aureobasidin A on Toxoplasma gondii
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Products are for research use only. Not for human use. We do not sell to patients.
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