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aurantio-obtusin

Cat. No. M4692

All AbMole products are for research use only, cannot be used for human consumption.

aurantio-obtusin Structure
Size Price Availability Quantity
1mg USD 50  USD50 In stock
5mg USD 75  USD75 In stock
10mg USD 120  USD120 In stock
20mg USD 180  USD180 In stock
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Quality Control & Documentation
Biological Activity

Aurantio-obtusin is an anthraquinone compound isolated from cassia seeds, which has anti-inflammatory, antioxidant, anticoagulant and antihypertensive effects. Aurantio-obtusin is a potential novel vasodilator for systemic arterial relaxation via endothelial PI3K/AKT/ ENOS-dependent signaling pathway in rats. Aurantio-obtusin inhibits IgE mediated mast cells and allergic reactions in allergic models, which has the potential to study allergy-related diseases.

Chemical Information
Molecular Weight 330.29
Formula C17H14O7
CAS Number 67979-25-3
Form Solid
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Fei Zhou, et al. Aurantio-Obtusin Attenuates Non-Alcoholic Fatty Liver Disease Through AMPK-Mediated Autophagy and Fatty Acid Oxidation Pathways

[2] Manjiang Hu, et al. Aurantio-obtusin induces hepatotoxicity through activation of NLRP3 inflammasome signaling

[3] Cong-Ying Guo, et al. Aurantio-obtusin improves obesity and insulin resistance induced by high-fat diet in obese mice

[4] Shun-Li Xiao, et al. The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin

[5] Ki Sun Kwon, et al. Aurantio-obtusin, an anthraquinone from cassiae semen, ameliorates lung inflammatory responses

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