Free shipping on all orders over $ 500

Atrasentan

Cat. No. M21788

All AbMole products are for research use only, cannot be used for human consumption.

Atrasentan Structure
Synonym:

ABT-627

Size Price Availability Quantity
5mg USD 120  USD120 In stock
10mg USD 170  USD170 In stock
25mg USD 340  USD340 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Atrasentan is a selective, orally active endothelin A (ETA) receptor antagonist. It can be used in studies related to glomerular disease and diabetic nephropathy.

Chemical Information
Molecular Weight 542.69
Formula C29H38N2O6S
CAS Number 173937-91-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] J David Smeijer, et al. JACC Heart Fail. Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident Heart Failure

[2] David C Wheeler, et al. Nephrol Dial Transplant. The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics

[3] Jesus Egido, et al. Expert Opin Investig Drugs. Atrasentan for the treatment of diabetic nephropathy

[4] Peter Norman. Curr Opin Investig Drugs. Atrasentan Abbott

Related Endothelin Receptor Products
A-127722 

A-127722 is A 2, 4-dialarylpyrrolidine-3-carboxylic acid ETA selective endothelin receptor (ET receptor) antagonist with IC50 value of 0.36 nM.

Endothelin 1 (swine, human) (TFA)

Endothelin 1 (swine, human) (TFA) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.

Atrial Natriuretic Peptide (ANP) (1-28), rat

Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

[Asn18] Endothelin-1, human

[Asn18] Endothelin-1, human is a peptide.

[Lys4] Sarafotoxin S6c

[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor.

  Catalog
Abmole Inhibitor Catalog




Keywords: Atrasentan, ABT-627 supplier, Endothelin Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.