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AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells.
| Molecular Weight | 488.33 |
| Formula | C22H22BrN3O5 |
| CAS Number | 211364-06-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 25 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[1] Jessica J Sánchez-García, et al. IUCrdata. 4,5-Diferrocenyl-1,2-di-thiole-3-thione
[5] C Näther, et al. Acta Crystallogr C. 4,4'-Bipyridine dihydrate at 130 K
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