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Aselizumab (HuDreg-55) is an humanized IgG4 mAb against L-selectin. However, L-selectin (CD62L) is a cell adhesion molecule expressed on circulating neutrophils. It regulates migrating cells to chemotaxis towards the site of injury. Aselizumab may be account for a high rate of infections and leucopenia after truma.
| CAS Number | 395639-53-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] M Bayés, et al. Methods Find Exp Clin Pharmacol. Gateways to clinical trials
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