Free shipping on all orders over $ 500

Arteannuin B

Cat. No. M10360
Arteannuin B Structure
Size Price Availability Quantity
5mg USD 300  USD300 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM. Artemisinin is the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae).

Chemical Information
Molecular Weight 248.32
Formula C15H20O3
CAS Number 50906-56-4
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage 2-8°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Javeed Ur Rasool, et al. Bioorg Chem. Site selective synthesis and anti-inflammatory evaluation of Spiro-isoxazoline stitched adducts of arteannuin B

[2] Yunjia Hu, et al. Front Cell Infect Microbiol. Artemether, Artesunate, Arteannuin B, Echinatin, Licochalcone B and Andrographolide Effectively Inhibit SARS-CoV-2 and Related Viruses In Vitro

[3] Yanqing Wang, et al. Pharmaceutics. Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches

[4] Sophia J Lang, et al. Phytomedicine. Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients

[5] Chao Zhang, et al. Asian Pac J Trop Med. Effects of arteannuin B, arteannuic acid and scopoletin on pharmacokinetics of artemisinin in mice

Related Anti-infection Products
1,2,3,4-Tetrahydronorharman-1-one

1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge.

Acetylalkannin

Acetylalkannin (Alkannin acetate) is an isohexenylnaphthazarin pigment isolated from Arnebia euchroma with antimicrobial and cytotoxic activities.

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein).

LCMV GP (61-80)

LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), and corresponds to amino acids 61-80.

Histone H4 (2-21)

Histone H4 (2-21) is the core histones associated with chromatinization of herpes simplex virus 1 (HSV-1) genomes.

  Catalog
Abmole Inhibitor Catalog




Keywords: Arteannuin B supplier, Anti-infection, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.