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Arotinolol

Cat. No. M30480

All AbMole products are for research use only, cannot be used for human consumption.

Arotinolol Structure

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Quality Control & Documentation
Biological Activity

Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases.

Chemical Information
Molecular Weight 371.54
Formula C15H21N3O2S3
CAS Number 68377-92-4
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pingping Huang, et al. Front Cardiovasc Med. Effect of arotinolol on chronic heart failure: A systematic review and meta-analysis of randomized controlled trials

[2] Zheyuan Qian, et al. J Pharm Biomed Anal. Enantiospecific determination of arotinolol in rat plasma by LC-MS/MS: application to a stereoselective pharmacokinetic study

[3] Wugang Zhou, et al. PLoS One. Mechanisms of improved aortic stiffness by arotinolol in spontaneously hypertensive rats

[4] J Zhao, et al. Can J Physiol Pharmacol. Arotinolol is a weak partial agonist on beta 3-adrenergic receptors in brown adipocytes

[5] S Morimoto, et al. Clin Exp Pharmacol Physiol. Effects of arotinolol, an alpha- and beta-adrenoceptor antagonist, on renin release from rat kidney cortical slices

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Keywords: Arotinolol supplier, Adrenergic Receptor, inhibitors, activators

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