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(Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 (Nona-L-arginine; 5-10 μM) acetate provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC50=0.78 μM). Following kainic acid exposure, (Arg)9 acetate is neuroprotective, but less effective than in the glutamic acid model (IC50=0.81 μM). (Arg)9 acetate also shows neuroprotection following in vitro ischemia (IC50=6 μM).
Molecular Weight | 1483.74 |
Formula | C56H114N36O12 |
CAS Number | 143413-47-2 (free base) |
Solubility (25°C) | Water 50 mg/mL |
Storage | Store at ≤ -20°C, dry, sealed |
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