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APETx2 TFA is sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC50 of 63 nM.
Sequence: Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp (Disulfide bridge:Cys4-Cys37;Cys6-Cys30;Cys20-Cys38)
| Molecular Weight | 4675.02 |
| Formula | C198H281F3N54O62S6 |
| CAS Number | 713544-47-9 (free base) |
| Solubility (25°C) | Water |
| Storage | Powder -20°C, protect from light, dry, sealed |
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