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Anti-human HER-2 mAb

Cat. No. M11384

All AbMole products are for research use only, cannot be used for human consumption.

Anti-human HER-2 mAb Structure
Size Price Availability Quantity
500ug USD 450  USD450 In stock
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Quality Control & Documentation
  • Purity: >98% , Endotoxin <2EU/mg
  • COA
  • MSDS
Biological Activity

Expression host: CHO cells
Endotoxin: <2EU/mg
Purity: > 98%
Concentration: 1 mg/mL
Storage and stability: stored at -20℃ for 6 months after opening, stored at -80℃ for 12 months. Avoid repeated freezing and thawing

Biological activity: HER2, also known as ErbB2, is a member of the human epidermal growth factor receptor family and plays an important role in signal transduction. Her-2/ NEU protein mediated signal transduction pathway mainly includes Ras/Raf/ mitin-activated protein kinase (MAPK) pathway and phosphatidylinositol pathway. 3 hydroxyl kinase (P13K)/Akt pathway, signal transduction and transcriptional activation (STAT) pathway and PLC pathway. 2 Expression of HER-2 / NEu protein in gastric cancer and its influencing factors Her-2/ NEu protein is usually only expressed in fetal period, and is only expressed at low level in very few tissues after adulthood.

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. An Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H 2 Mab-19 Exerts Antitumor Activity in Mouse Colon Cancer Xenografts

[2] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. H 2 Mab-19 Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody Therapy Exerts Antitumor Activity in Pancreatic Cancer Xenograft Models

[3] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H 2 Mab-41 Exerts Antitumor Activity in a Mouse Xenograft Model of Colon Cancer

[4] Mohammad Mehdi Amiri, et al. Iran J Immunol. Development of a Novel Inhibitory Chimeric Anti-HER2 Monoclonal Antibody

[5] Shinji Yamada, et al. Monoclon Antib Immunodiagn Immunother. Establishment of H 2 Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer

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