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The angiotensin-converting enzyme (ACE) is a dipeptidyl-carboxypeptidase which exists in somatic and testicular isoforms with zinc binding motif HEXXH in their active site.
ACE regulates blood pressure through renin-angiotensin system. ACE plays a critical role in fertilization by releasing the proteins anchored to glycosylphosphatidylinositol (GPI) in sperm membrane.
Angiotensin converting enzyme can been used for measuring inhibitory effect of egg white protein hydrolysates on ACE activity by high performance liquid chromatography (HPLC) and in releasing GPI anchored protein in vitro in few cell lines like HeLa, HEK293 and in vivo in mice sperm.
| CAS Number | 9015-82-1 |
| Form | Lyophilized powder |
| Storage | -20°C, sealed |
| Related Enzymes & Coenzymes Products |
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| Butyryl Cholinesterase (Horse serum)
Butyryl Cholinesterase is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE) but has different substrate specificity and inhibitor sensitivity. The enzyme is a tetrameric glycoprotein composed of four identical subunits (110 kDa each) and is also known as pseudocholinesterase. It is synthesised in the liver and distributed in blood, neuromuscular junction synapses, glial cells and white matter axons. |
| β-Glucosidase (from Almonds)
β-Glucosidase is the main component of glycoside hydrolases that hydrolyse Glucoside into glucose and other constituents. β-Glucosidase works by breaking down fibre-rich cell walls to release and utilise the nutrients such as proteins and starch contained therein, while at the same time degrading the fibre to reducing sugars that can be digested and assimilated by the body of the animal. |
| Diaphorase
Diaphorase has been used in a study to assess the protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. |
| Lipase (pocine pancreas)
Lipase is a class of enzymes with a variety of catalytic abilities that catalyse the hydrolysis of ester bonds at the lipid-water interface, and can catalyse the hydrolysis, alcoholysis, esterification, transesterification and reverse synthesis reactions of triacylglycerol esters and some other water-insoluble esters. Lipase can be used in biochemical research, analysis of prostaglandin esters and triglycerides in serum, and fat analysis. |
| Carbonic anhydrase (Bovine erythrocytes)
Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. |
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