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Nattokinase is an enzyme extracted and purified from a Japanese food called nattō. Nattokinase is a serine protease of the subtilisin family. It exhibits a strong fibrinolytic activity. A 2009 study showed that nattokinase may be effective in catabolism of toxic amyloid fibrils associated with Alzheimer's Disease, as well as the insulin fibrils associated with diabetes and the prion peptide fibrils associated with prion diseases.
J Diabetes. 2023 Jul 4.
Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy
Nattokinase purchased from AbMole
Invest Ophthalmol Vis Sci. 2021 May 3;62(6):25.
Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation
Nattokinase purchased from AbMole
| Molecular Weight | 463.5 |
| Formula | C23H28ClN3O5 |
| CAS Number | 133876-92-3 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Enzymes & Coenzymes Products |
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| Sulfatase (from Helix pomatia)
Sulfatase (from Helix pomatia) facilitates the synthesis of thiohydroximates. It causes the hydrolysis of β-naphthyl sulfate much faster than a-naphthyl sulfate and possesses regiospecificity in the hydrolysis of ortho and para substituted phenyl sulfates. |
| α-Glucosidase (from yeast)
α-Glucosidase is a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-glucosidase is used for the determination of α-amylase and the synthesis of various 1′-O-sucrose and 1-O-fructose esters. It was also used in the measurement of glycosidase inhibition. |
| Peroxidase (Horseradish)
Peroxidase (Horseradish) involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases. |
| Trypsin (bovine pancreas)
Trypsin is a serine protease in the digestive system of human and animals. The main function of this enzyme is to hydrolyze proteins into smaller peptides or even amino acids. |
| Neuraminidase
Neuraminidase is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. |
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Products are for research use only. Not for human use. We do not sell to patients.
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